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Home - Products - Cell Cycle/DNA Damage - Topoisomerase - Proscillaridin A

Proscillaridin A

CAS No. 466-06-8

Proscillaridin A ( —— )

Catalog No. M24416 CAS No. 466-06-8

Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Proscillaridin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
  • Description
    Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    topoisomerase I;topoisomerase II
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    466-06-8
  • Formula Weight
    530.7
  • Molecular Formula
    C30H42O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL?(188.45 mM;?Need ultrasonic)
  • SMILES
    O[C@@]([C@@]1(CC2)C)(CC[C@@H]1C(C=C3)=COC3=O)[C@@](CCC4=C[C@@H](O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)CC6)([H])[C@@]2([H])[C@]46C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bielawski K, et al. Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A.Biol Pharm Bull. 2006 Jul;29(7):1493-7.
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