Proscillaridin A ( —— )

Catalog No. M24416 CAS No. 466-06-8

Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Proscillaridin A
Note

Research use only, not for human use.
Brief Description

Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
Description

Proscillaridin A is a natural product.It is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

Topoisomerase
Recptor

topoisomerase I;topoisomerase II
Research Area

——
Indication

——

Chemical Information

CAS Number

466-06-8
Formula Weight

530.7
Molecular Formula

C30H42O8
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL?(188.45 mM;?Need ultrasonic)
SMILES

O[C@@]([C@@]1(CC2)C)(CC[C@@H]1C(C=C3)=COC3=O)[C@@](CCC4=C[C@@H](O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)CC6)([H])[C@@]2([H])[C@]46C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Bielawski K, et al. Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A.Biol Pharm Bull. 2006 Jul;29(7):1493-7.

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